Term Name: | U4_snRNA |
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Synonyms: | small nuclear RNA U4, snRNA U4, U4 small nuclear RNA, U4 snRNA |
Definition: | U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6. |
Ontology: | Sequence Ontology [SO:0000393] |