Term Name: T-cell surface glycoprotein CD8 alpha chain
Synonyms: CD8A, Lyt-2, Lyt2, MAL, T-cell surface glycoprotein Lyt-2, T-lymphocyte differentiation antigen T8/Leu-2
Definition: A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain.
Ontology: Cell Ontology [PR:000001084]

Relationships
is a type of: protein
has subtype: T-cell surface glycoprotein CD8 alpha chain isoform 1
inverse has_low_plasma_membrane_amount: CD8_alpha-low Langerhans cell
inverse has_plasma_membrane_part: CD8-alpha alpha positive, gamma-delta intraepithelial T cell CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell CD8_alpha-positive CD11b-negative dendritic cell CD8_alpha-positive plasmactyoid dendritic cell CD8alpha-positive thymic conventional dendritic cell dermal dendritic cell
inverse lacks_plasma_membrane_part: activated CD4-negative, CD8-negative type I NK T cell basophil progenitor cell CD4-negative CD8-negative gamma-delta intraepithelial T cell CD4-negative, CD8-negative type I NK T cell CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell CD4-positive CD11b-positive dendritic cell CD4-positive, alpha-beta thymocyte CD8_alpha-negative CD11b-negative dendritic cell CD8_alpha-negative plasmactyoid dendritic cell CD8alpha-negative thymic conventional dendritic cell common dendritic progenitor DN1 thymic pro-T cell eosinophil progenitor cell erythroblast erythroid progenitor cell, mammalian granulocyte group 2 innate lymphoid cell, mouse hematopoietic multipotent progenitor cell hematopoietic oligopotent progenitor cell, lineage-negative hematopoietic stem cell Kit and Sca1-positive hematopoietic stem cell langerin-negative, CD103-negative lymph node dendritic cell langerin-positive lymph node dendritic cell mast cell progenitor megakaryocyte progenitor cell natural helper lymphocyte pre-conventional dendritic cell proerythroblast reticulocyte