Term Name: CD4 molecule
Synonyms: CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Definition: A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.
Ontology: Cell Ontology [PR:000001004]

Relationships
is a type of: protein
inverse has_low_plasma_membrane_amount: CD4-intermediate, CD8-positive double-positive thymocyte immature NK T cell stage I
inverse has_plasma_membrane_part: activated CD4-positive type I NK T cell CD4-positive CD11b-positive dendritic cell CD4-positive type I NK T cell CD4-positive type I NK T cell secreting interferon-gamma CD4-positive type I NK T cell secreting interleukin-4 CD4-positive, alpha-beta T cell CD4-positive, alpha-beta thymocyte CD8_alpha-negative plasmactyoid dendritic cell CD8_alpha-positive plasmactyoid dendritic cell double-positive, alpha-beta thymocyte effector CD4-positive, alpha-beta T cell
inverse lacks_plasma_membrane_part: activated CD4-negative, CD8-negative type I NK T cell basophil progenitor cell CD4-negative CD8-negative gamma-delta intraepithelial T cell CD4-negative, CD8-negative type I NK T cell CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 CD4-negative, CD8-negative, alpha-beta intraepithelial T cell Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell CD8-positive, alpha-beta T cell CD8-positive, alpha-beta thymocyte CD8_alpha-negative CD11b-negative dendritic cell CD8_alpha-positive CD11b-negative dendritic cell common dendritic progenitor DN1 thymic pro-T cell DN2 thymocyte DN3 thymocyte DN4 thymocyte double negative thymocyte effector CD8-positive, alpha-beta T cell eosinophil progenitor cell erythroblast erythroid progenitor cell, mammalian gamma-delta thymocyte group 2 innate lymphoid cell, mouse hematopoietic multipotent progenitor cell hematopoietic oligopotent progenitor cell, lineage-negative hematopoietic stem cell immature single positive thymocyte langerin-negative, CD103-negative lymph node dendritic cell langerin-positive lymph node dendritic cell mast cell progenitor megakaryocyte progenitor cell pre-conventional dendritic cell proerythroblast reticulocyte