Term Name: | hepatic stellate cell proliferation |
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Synonyms: | hepatic perisinusoidal cell proliferation, Ito cell proliferation, perisinusoidal cell proliferation |
Definition: | The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. |
Ontology: | GO: Biological Process [GO:1990922] QuickGO AmiGO |