Term Name:	PCSK9-LDLR complex
Synonyms:	PCSK9.LDLR complex, PCSK9/LDL-R complex, PCSK9:EGF-A complex, PCSK9:low-density lipoprotein receptor complex
Definition:	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.
Ontology:	GO: Cellular Component [GO:1990666]    QuickGO    AmiGO