Term Name: | eif4e-cup complex |
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Synonyms: | eukaryotic translation initiation factor 4E-cup complex |
Definition: | A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo. |
Ontology: | GO: Cellular Component [GO:1990500] QuickGO AmiGO |