Term Name: | snRNA 2,2,7-trimethylguanosine (TMG) capping |
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Synonyms: | snRNA 2,2,7-trimethylguanosine (TMG) cap formation, snRNA 5'-end processing |
Definition: | The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed U6 snRNA is also TMG capped. |
Ontology: | GO: Biological Process [GO:1990273] QuickGO AmiGO |