Term Name: | transcription-coupled nucleotide-excision repair, DNA damage recognition complex |
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Synonyms: | |
Definition: | A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. |
Ontology: | GO: Cellular Component [GO:1990250] QuickGO AmiGO |