Term Name: | uniplex complex |
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Synonyms: | mitochondrial uniporter complex, mitochondrial uniporter holocomplex |
Definition: | A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE. |
Ontology: | GO: Cellular Component [GO:1990246] QuickGO AmiGO |