Term Name: | maintenance of unfolded protein involved in ERAD pathway |
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Synonyms: | chaperone holdase activity, ERAD chaperone-like activity, holdase activity, maintenance of unfolded protein during ERAD, maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation, maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway, maintenance of unfolded protein involved in ER-associated degradation pathway |
Definition: | Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome. |
Ontology: | GO: Biological Process [GO:1904378] QuickGO AmiGO |