Term Name: | Cyc8(Ssn6)-Tup1 general repressor complex |
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Synonyms: | Tup11/Tup12 repressor complex |
Definition: | A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters. |
Ontology: | GO: Cellular Component [GO:0160051] QuickGO AmiGO |