Term Name: | very-long-chain 3-oxoacyl-CoA reductase activity |
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Synonyms: | |
Definition: | Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH. This reaction is the second (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit. |
Ontology: | GO: Molecular Function [GO:0141040] QuickGO AmiGO |