Term Name:	secondary piRNA processing
Synonyms:	ping-pong amplification, ping-pong derived piRNA, secondary piRNA biogenesis, secondary PIWI-associated RNA processing
Definition:	A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4.
Ontology:	GO: Biological Process [GO:0140965]    QuickGO    AmiGO