Term Name: | target-directed miRNA degradation |
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Synonyms: | target-directed microRNA degradation, TDMD |
Definition: | The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases. |
Ontology: | GO: Biological Process [GO:0140958] QuickGO AmiGO |