Term Name: | opioid growth factor receptor signaling pathway |
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Synonyms: | |
Definition: | The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A). |
Ontology: | GO: Biological Process [GO:0140626] QuickGO AmiGO |