Term Name: | necroptotic signaling pathway |
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Synonyms: | necroptosis signaling, necroptosis signaling pathway, necroptotic signal transduction, necroptotic signalling pathway |
Definition: | The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. |
Ontology: | GO: Biological Process [GO:0097527] QuickGO AmiGO |