Term Name: | perinucleolar compartment |
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Synonyms: | perinucleolar region |
Definition: | The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC. |
Ontology: | GO: Cellular Component [GO:0097356] QuickGO AmiGO |