Term Name: | endothelial tip cell fate specification |
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Synonyms: | angiogenic tip cell fate specification |
Definition: | The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. |
Ontology: | GO: Biological Process [GO:0097102] QuickGO AmiGO |