Term Name: | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity |
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Synonyms: | |
Definition: | Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. |
Ontology: | GO: Molecular Function [GO:0072586] QuickGO AmiGO |