Term Name: | BAT3 complex |
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Synonyms: | Bag6 complex, BAG6-UBL4A-TRC35 complex, BAT3-TRC35-UBL4A complex |
Definition: | A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A. |
Ontology: | GO: Cellular Component [GO:0071818] QuickGO AmiGO |