Term Name: | LUBAC complex |
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Synonyms: | |
Definition: | A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. |
Ontology: | GO: Cellular Component [GO:0071797] QuickGO AmiGO |