Term Name: | U12-type prespliceosome |
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Synonyms: | AT-AC prespliceosome, mammalian U12-type spliceosomal complex A, minor prespliceosome, yeast U12-type spliceosomal complex B |
Definition: | A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. |
Ontology: | GO: Cellular Component [GO:0071015] QuickGO AmiGO |