Term Name: | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
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Synonyms: | heparan glucuronyltransferase II activity, N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity, N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity, UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Definition: | Catalysis of the reaction: 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + H+ + UDP. |
Ontology: | GO: Molecular Function [GO:0050509] QuickGO AmiGO |