Term Name: | histone H4K16 deacetylase activity, NAD-dependent |
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Synonyms: | NAD-dependent histone deacetylase activity (H4-K16 specific), NAD-dependent histone H4-K16 deacetylase activity, NAD-dependent histone H4K16 deacetylase activity |
Definition: | Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + NAD+ + H2O = histone H4 L-lysine (position 16) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H4K16 to NAD, producing nicotinamide. |
Ontology: | GO: Molecular Function [GO:0046970] QuickGO AmiGO |