Term Name: | negative regulation of mitotic metaphase/anaphase transition |
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Synonyms: | down regulation of mitotic metaphase/anaphase transition, down-regulation of mitotic metaphase/anaphase transition, downregulation of mitotic metaphase/anaphase transition, inhibition of mitotic metaphase/anaphase transition |
Definition: | Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. |
Ontology: | GO: Biological Process [GO:0045841] QuickGO AmiGO |