Term Name: | proton-transporting ATP synthase complex |
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Synonyms: | F1-F0 complex, hydrogen-translocating F-type ATPase complex, hydrogen-transporting ATP synthase complex, proton-transporting F-type ATPase complex |
Definition: | A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. |
Ontology: | GO: Cellular Component [GO:0045259] QuickGO AmiGO |