Term Name: | protein insertion into ER membrane |
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Synonyms: | integral ER membrane protein localization, integral ER membrane protein positioning, localization of protein in ER membrane, positioning of protein in ER membrane, protein insertion into endoplasmic reticulum membrane, protein-endoplasmic reticulum insertion, protein-ER insertion |
Definition: | The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. |
Ontology: | GO: Biological Process [GO:0045048] QuickGO AmiGO |