Term Name: | endoplasmic reticulum quality control compartment |
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Synonyms: | ER quality control compartment, ER-derived quality control compartment, ERQC |
Definition: | A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins. |
Ontology: | GO: Cellular Component [GO:0044322] QuickGO AmiGO |