Term Name: | insulin receptor substrate binding |
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Synonyms: | insulin receptor substrate [protein] binding, IRS [protein] binding, IRS binding |
Definition: | Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. |
Ontology: | GO: Molecular Function [GO:0043560] QuickGO AmiGO |