Term Name: | ERBB4-EGFR signaling pathway |
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Synonyms: | ERBB1-ERBB4 signaling pathway, ERBB4-EGFR signalling pathway, HER1-HER4 signaling pathway |
Definition: | The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. |
Ontology: | GO: Biological Process [GO:0038137] QuickGO AmiGO |