Term Name:	hippo signaling
Synonyms:	hippo signal transduction, hippo signaling cascade, hippo signaling pathway, hippo signalling cascade, Salvador-Warts-Hippo signaling pathway, SWH pathway
Definition:	An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation.
Ontology:	GO: Biological Process [GO:0035329]    QuickGO    AmiGO