Term Name: | NAD-dependent protein lysine deacetylase activity |
---|---|
Synonyms: | NAD(+)-dependent protein deacetylase, NAD(+)-dependent protein deacylase, NAD-dependent protein deacetylase activity, protein acetyllysine N-acetyltransferase, protein lysine deacetylase, protein lysine deacylase |
Definition: | Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide. |
Ontology: | GO: Molecular Function [GO:0034979] QuickGO AmiGO |