Term Name: | ribonuclease T2 activity |
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Synonyms: | acid ribonuclease activity, acid RNase activity, base-non-specific ribonuclease activity, Escherichia coli ribonuclease I' ribonuclease PP2 activity, Escherichia coli ribonuclease II activity, non-base specific ribonuclease activity, nonbase-specific RNase activity, nonspecific RNase activity, ribonnuclease (non-base specific) activity, ribonuclease (non-base specific) activity, ribonuclease II activity, ribonuclease M activity, ribonuclease N2 activity, ribonuclease PP3 activity, ribonuclease U4 activity, ribonucleate 3'-oligonucleotide hydrolase activity, ribonucleate nucleotido-2'-transferase (cyclizing) activity, RNAase CL activity, RNase (non-base specific) activity, RNase II activity, RNase M activity, RNase Ms activity, RNase T2 activity |
Definition: | Catalysis of the reaction: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H+. This reaction is a two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. |
Ontology: | GO: Molecular Function [GO:0033897] QuickGO AmiGO |