Term Name: | mitotic checkpoint complex |
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Synonyms: | MCC |
Definition: | A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20. |
Ontology: | GO: Cellular Component [GO:0033597] QuickGO AmiGO |