Term Name: | TSC1-TSC2 complex |
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Synonyms: | tuberin-hamartin complex, tuberous sclerosis complex |
Definition: | A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. |
Ontology: | GO: Cellular Component [GO:0033596] QuickGO AmiGO |