Term Name: | tumor necrosis factor production |
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Synonyms: | cachectin production, TNF alpha biosynthesis, TNF biosynthesis, TNF biosynthetic process, TNF production, TNF-alpha biosynthesis, TNF-alpha biosynthetic process, TNF-alpha production, Tnfa production, tumor necrosis factor anabolism, tumor necrosis factor biosynthesis, tumor necrosis factor biosynthetic process, tumor necrosis factor formation, tumor necrosis factor secretion, tumor necrosis factor synthesis, tumor necrosis factor-alpha production |
Definition: | The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. |
Ontology: | GO: Biological Process [GO:0032640] QuickGO AmiGO |