Term Name: | purine-rich negative regulatory element binding |
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Synonyms: | PNR element binding |
Definition: | Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. |
Ontology: | GO: Molecular Function [GO:0032422] QuickGO AmiGO |