Term Name: | DNA integrity checkpoint signaling |
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Synonyms: | DNA integrity checkpoint, signal transduction involved in DNA integrity checkpoint |
Definition: | A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes. |
Ontology: | GO: Biological Process [GO:0031570] QuickGO AmiGO |