Term Name: | translesion synthesis |
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Synonyms: | bypass DNA synthesis |
Definition: | The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. |
Ontology: | GO: Biological Process [GO:0019985] QuickGO AmiGO |