Term Name: | receptor-mediated endocytosis |
---|---|
Synonyms: | receptor mediated endocytosis |
Definition: | An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. |
Ontology: | GO: Biological Process [GO:0006898] QuickGO AmiGO |