Term Name: | GPI anchor metabolic process |
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Synonyms: | glycosylphosphatidylinositol metabolic process, glycosylphosphatidylinositol metabolism, GPI anchor metabolism, GPI/GSI anchor metabolic process, GPI/GSI anchor metabolism |
Definition: | The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain. |
Ontology: | GO: Biological Process [GO:0006505] QuickGO AmiGO |