Term Name: | mitochondrial permeability transition pore complex |
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Synonyms: | mitochondrial PT pore complex, MPTP complex, PTPC |
Definition: | A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). |
Ontology: | GO: Cellular Component [GO:0005757] QuickGO AmiGO |