Term Name: | TIM23 mitochondrial import inner membrane translocase complex |
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Synonyms: | mitochondrial inner membrane pre-sequence translocase complex, mitochondrial inner membrane presequence translocase complex, mitochondrial inner membrane translocase complex, Tim23 complex |
Definition: | The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. |
Ontology: | GO: Cellular Component [GO:0005744] QuickGO AmiGO |