Term Name: | nuclear pre-replicative complex |
---|---|
Synonyms: | eukaryotic pre-replicative complex, pre-RC, pre-replicative complex |
Definition: | A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins. |
Ontology: | GO: Cellular Component [GO:0005656] QuickGO AmiGO |