Term Name: | membrane attack complex |
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Synonyms: | MAC, membrane attack complex protein alphaM chain, membrane attack complex protein beta2 chain, TCC, terminal complement complex |
Definition: | A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. |
Ontology: | GO: Cellular Component [GO:0005579] QuickGO AmiGO |