Term Name: | ribonuclease III activity |
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Synonyms: | pre-mRNA 3'-end processing endonuclease, ribonuclease 3 activity, RNase III activity |
Definition: | Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt. |
Ontology: | GO: Molecular Function [GO:0004525] QuickGO AmiGO |