Term Name: | GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity |
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Synonyms: | GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity, GDP-mannose-oligosaccharide-lipid mannosyltransferase activity, GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity, glycolipid 2-alpha-mannosyltransferase activity, guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity, oligosaccharide-lipid mannosyltransferase activity |
Definition: | Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. |
Ontology: | GO: Molecular Function [GO:0004377] QuickGO AmiGO |