Term Name: | 2-isopropylmalate synthase activity |
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Synonyms: | 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity, acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), alpha-IPM synthetase activity, alpha-isopropylmalate synthase activity, alpha-isopropylmalate synthetase activity, alpha-isopropylmalic synthetase activity, isopropylmalate synthase activity, isopropylmalate synthetase activity |
Definition: | Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H+. |
Ontology: | GO: Molecular Function [GO:0003852] QuickGO AmiGO |