Term Name: | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent |
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Synonyms: | cross presentation, cross-presentation, exogenous peptide antigen processing and presentation via MHC class I, TAP-independent, TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent exogenous peptide antigen processing and presentation via MHC class I |
Definition: | The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules. |
Ontology: | GO: Biological Process [GO:0002480] QuickGO AmiGO |