Term Name: | peripheral B cell receptor editing |
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Synonyms: | peripheral B lymphocyte receptor editing, peripheral B-cell receptor editing, peripheral B-lymphocyte receptor editing |
Definition: | The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation. |
Ontology: | GO: Biological Process [GO:0002345] QuickGO AmiGO |